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CXL in Nashville, TN

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About Corneal Cross-Linking

Wang Vision Institute was one of the nations FDA clinical trial centers for research for cross-linking.

Our Wang Vision Institute ophthalmologists and their dedicated team are proud to offer our patients in Nashville, TN and beyond an innovative new procedure to treat and manage keratoconus called corneal cross-linking. Corneal cross-linking, also called UV riboflavin CXL, addresses keratoconus by strengthening the cornea, resulting in a reduction of the risk of its progressive weakening and the patient's eventual loss of sight. This treatment works by combining riboflavin (Vitamin B2) drops and UV light to enhance the cornea and stimulate the growth of its internal collagen cross-links. Wang Vision Institute was the first optical care center in the state of Tennessee to perform corneal cross-linking for patients with keratoconus, and our eye surgeons continue to improve the eye health and vision of those who trust their care to our capable team.

Best Candidates FOR CXL

Typically, the ideal candidate for corneal cross-linking is a keratoconus patient aged 14 or older. While people may receive this procedure at any age, many ophthalmologists agree that early treatment is preferred for improved vision and lasting results. This is because young patients with keratoconus usually have not experienced a high degree of progression of the disease when compared to adults, making the condition easier to manage or even stop. Before we can fully determine your candidacy for the procedure, one of our eye surgeons will need to assess your eye health and medical history. This includes determining if you have had a documented progression of keratoconus over the past 12 – 18 months.

What To Expect

Corneal cross-linking is typically performed in an outpatient setting and is known to not cause any discomfort for the patient. To start, we will apply numbing eye drops to the eyes. Once you are fully numb, we will carefully remove the epithelium cells from the surface of your cornea and distribute the riboflavin eye drops (Photrexa). After about 15 – 30 minutes, the drops will fully absorb into the eye. From there, we will expose your eyeballs to the UV light, which will interact with the riboflavin to produce special oxygen molecules. These molecules will ultimately cause collagen fibers to develop within the cornea, making it stronger and hindering the progression of corneal weakening (keratoconus).


The general recovery period for a CXL surgery is 3 – 5 days. During this time, your treated eyes will be protected with a bandage contact lens. One of our doctors may prescribe anti-inflammatory eye drops for you to use for a predetermined amount of time as you heal. In many cases, patients receive relief from their keratoconus symptoms as early as a week following their procedure with their results continuing to improve up to 12 months post-op. Patients who receive this surgery will experience a frequent change in their eyeglass prescription until the condition of their cornea has fully stabilized.

Effective Treatment

CXL, more popularly known as corneal cross-linking, is an innovative new treatment that can produce positive, life-changing results for patients suffering from the effects of keratoconus. Along with protecting your vision, this procedure can also prevent Nashville, TN patients from requiring a corneal transplant later in their life. Our skilled eye surgeons, Dr. Wang and Dr. Frenkel, have performed a number of successful cross-linking treatments with Dr. Wang overseeing Tennessee's very first CXL procedure. If you think you may have keratoconus, we encourage you to get in touch with Wang Vision Institute at your earliest convenience.

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*Individual results are not guaranteed and may vary from person to person. Images may contain models.